NETWORK OPTIMIZATION IN THE BRAIN [I, 1991]: From C. elegans to Cerebral Cortex
dc.contributor.author | Cherniak, Christopher | en_US |
dc.date.accessioned | 2004-05-31T23:32:06Z | |
dc.date.available | 2004-05-31T23:32:06Z | |
dc.date.created | 2003-09 | en_US |
dc.date.issued | 2003-09-25 | en_US |
dc.description.abstract | How well do "Save wire" concepts from combinatorial network optimization theory fit as models for brain anatomy? One result concerns ganglion placement in the nervous system of C. elegans: Our exhaustive searches indicate that the actual layout of the ganglia in the roundworm requires less total interconnecting wirelength than any of the 40 million other possible layouts -- a predictive success story. For the corresponding, but combinatorially intractable, question of interconnection wire- minimization in placement of the areas on the cerebral cortex sheet, we tested instead an "Adjacency Rule": If components a and b are interconnected, then they are contiguous. If cortical components are placed to minimize total interconnection costs, one would expect conformation to this rule; we found strong support for both macaque and cat visual cortex, as well as C. elegans ganglia. [ MH49867 9/91 3.0 ] (UMIACS-TR-2003-92) | en_US |
dc.format.extent | 1509903 bytes | |
dc.format.mimetype | application/pdf | |
dc.identifier.uri | http://hdl.handle.net/1903/1310 | |
dc.language.iso | en_US | |
dc.relation.isAvailableAt | Digital Repository at the University of Maryland | en_US |
dc.relation.isAvailableAt | University of Maryland (College Park, Md.) | en_US |
dc.relation.isAvailableAt | Tech Reports in Computer Science and Engineering | en_US |
dc.relation.isAvailableAt | UMIACS Technical Reports | en_US |
dc.relation.ispartofseries | UM Computer Science Department; CS-TR-4524 | en_US |
dc.relation.ispartofseries | UMIACS; UMIACS-TR-2003-92 | en_US |
dc.title | NETWORK OPTIMIZATION IN THE BRAIN [I, 1991]: From C. elegans to Cerebral Cortex | en_US |
dc.type | Technical Report | en_US |
Files
Original bundle
1 - 1 of 1