The Relation of Diabetes, Impaired Fasting Blood Glucose, and Insulin Resistance to Left Ventricular Structure and Function in African Americans: The Jackson Heart Study

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dc.contributor.authorFox, E. R.
dc.contributor.authorSarpong, D. F.
dc.contributor.authorCook, J. C.
dc.contributor.authorSamdarshi, T. E.
dc.contributor.authorNagarajarao, H. S.
dc.contributor.authorLiebson, P. R.
dc.contributor.authorSims, M.
dc.contributor.authorHoward, G.
dc.contributor.authorGarrison, R.
dc.contributor.authorTaylor, H. A.
dc.date.accessioned2019-08-14T15:04:18Z
dc.date.available2019-08-14T15:04:18Z
dc.date.issued2011
dc.description.abstractOBJECTIVE We assessed the relation of diabetes and insulin resistance (IR) on left ventricular (LV) structure and function in African Americans. RESEARCH DESIGN AND METHODS Among those receiving echocardiograms in cycle 1 of the Jackson Heart Study, we assessed the sex-specific relation of fasting blood glucose (FBG), diabetes, and IR to LV structure and function, adjusting for age, systolic blood pressure, antihypertensive medications, and BMI. RESULTS Among 2,399 participants, LV mass index (Pwomen = 0.0002 and Pmen = 0.02), posterior wall thickness (Pwomen = 0.01 and Pmen = 0.05), and interventricular septal wall thickness (Pwomen = 0.01) were related to FBG categories. Among those with normal FBG and no diabetes, concentric remodeling and low ejection fraction in women and LV mass index and posterior wall thickness in men were related to IR. CONCLUSIONS In the largest study of its kind in a community-based cohort of African Americans, we found a relation of FBG category and IR to LV structure and function.
dc.description.urihttp://dx.doi.org/10.2337/dc10-0838
dc.identifierhttps://doi.org/10.13016/uy6s-ljqg
dc.identifier.citationFox, E. R. and Sarpong, D. F. and Cook, J. C. and Samdarshi, T. E. and Nagarajarao, H. S. and Liebson, P. R. and Sims, M. and Howard, G. and Garrison, R. and Taylor, H. A. (2011) The Relation of Diabetes, Impaired Fasting Blood Glucose, and Insulin Resistance to Left Ventricular Structure and Function in African Americans: The Jackson Heart Study. Diabetes Care, 34 (2). pp. 507-509.
dc.identifier.issn0149-5992
dc.identifier.otherEprint ID 3048
dc.identifier.urihttp://hdl.handle.net/1903/23667
dc.subjectDiabetes
dc.subjectResearch
dc.subjectdiabetes
dc.subjectinsulin resistance
dc.subjectAfrican Americans
dc.subjectJackson Heart Study
dc.titleThe Relation of Diabetes, Impaired Fasting Blood Glucose, and Insulin Resistance to Left Ventricular Structure and Function in African Americans: The Jackson Heart Study
dc.typeArticle

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