Capsule Migration and Deformation in a Converging Micro-Capillary

dc.contributor.authorWang, Yiyang
dc.contributor.authorDimitrakopoulos, Panagiotis
dc.date.accessioned2023-11-06T19:04:21Z
dc.date.available2023-11-06T19:04:21Z
dc.date.issued2021-03-03
dc.description.abstractThe lateral migration of elastic capsules towards a microchannel centerline plays a major role in industrial and physiological processes. Via our computational investigation, we show that a constriction connecting two straight microchannels facilitates the lateral capsule migration considerably, which is relatively slow in straight channels. Our work reveals that the significant cross-streamline migration inside the constriction is dominated by the strong hydrodynamic forces due to the capsule size. However, in the downstream straight channel, the increased interfacial deformation at higher capillary numbers or a lower viscosity ratio and lower membrane hardness results in increased lateral cross-streamline migration. Thus, our work highlights the different migration mechanisms occurring over curved and straight streamlines.
dc.description.urihttps://doi.org/10.3390/pr9030452
dc.identifierhttps://doi.org/10.13016/dspace/fc2y-lzxj
dc.identifier.citationWang, Y.; Dimitrakopoulos, P. Capsule Migration and Deformation in a Converging Micro-Capillary. Processes 2021, 9, 452.
dc.identifier.urihttp://hdl.handle.net/1903/31271
dc.language.isoen_US
dc.publisherMDPI
dc.relation.isAvailableAtDigital Repository at the University of Marylanden_us
dc.relation.isAvailableAtUniversity of Maryland (College Park, MD)en_us
dc.relation.isAvailableAtA. James Clark School of Engineeringen_us
dc.relation.isAvailableAtChemical & Biomolecular Engineeringen_us
dc.subjectelastic capsule
dc.subjectmicrofluidics
dc.subjectstokes flow
dc.titleCapsule Migration and Deformation in a Converging Micro-Capillary
dc.typeArticle
local.equitableAccessSubmissionNo

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