Integrated analysis of lncRNA and mRNA repertoires in Marek’s disease infected spleens identifies genes relevant to resistance

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dc.contributor.authorYou, Zhen
dc.contributor.authorZhang, Qinghe
dc.contributor.authorLiu, Changjun
dc.contributor.authorSong, Jiuzhou
dc.contributor.authorYang, Ning
dc.contributor.authorLian, Ling
dc.date.accessioned2021-06-08T14:22:31Z
dc.date.available2021-06-08T14:22:31Z
dc.date.issued2019-03-28
dc.description.abstractMarek’s disease virus (MDV) is an oncogenic herpesvirus that can cause T-cell lymphomas in chicken. Long noncoding RNA (lncRNA) is strongly associated with various cancers and many other diseases. In chickens, lncRNAs have not been comprehensively identified. Here, we profiled mRNA and lncRNA repertoires in three groups of spleens from MDV-infected and non-infected chickens, including seven tumorous spleens (TS) from MDV-infected chickens, five spleens from the survivors (SS) without lesions after MDV infection, and five spleens from noninfected chickens (NS), to explore the underlying mechanism of host resistance in Marek’s disease (MD).en_US
dc.description.urihttps://doi.org/10.1186/s12864-019-5625-1
dc.identifierhttps://doi.org/10.13016/smsd-abwv
dc.identifier.citationYou, Z., Zhang, Q., Liu, C. et al. Integrated analysis of lncRNA and mRNA repertoires in Marek’s disease infected spleens identifies genes relevant to resistance. BMC Genomics 20, 245 (2019).en_US
dc.identifier.urihttp://hdl.handle.net/1903/27130
dc.language.isoen_USen_US
dc.publisherSpringer Natureen_US
dc.relation.isAvailableAtCollege of Agriculture & Natural Resourcesen_us
dc.relation.isAvailableAtAnimal & Avian Sciencesen_us
dc.relation.isAvailableAtDigital Repository at the University of Marylanden_us
dc.relation.isAvailableAtUniversity of Maryland (College Park, MD)en_us
dc.subjectChickenen_US
dc.subjectLong noncoding RNAen_US
dc.subjectMarek’s diseaseen_US
dc.subjectMD resistanceen_US
dc.titleIntegrated analysis of lncRNA and mRNA repertoires in Marek’s disease infected spleens identifies genes relevant to resistanceen_US
dc.typeArticleen_US

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