GWAS and fine-mapping of livability and six disease traits in Holstein cattle

dc.contributor.authorFreebern, Ellen
dc.contributor.authorSantos, Daniel J. A.
dc.contributor.authorFang, Lingzhao
dc.contributor.authorJiang, Jicai
dc.contributor.authorParker Gaddis, Kristen L.
dc.contributor.authorLiu, George E.
dc.contributor.authorVanRaden, Paul M.
dc.contributor.authorMaltecca, Christian
dc.contributor.authorCole, John B.
dc.contributor.authorMa, Li
dc.date.accessioned2021-06-04T16:31:34Z
dc.date.available2021-06-04T16:31:34Z
dc.date.issued2020-01-13
dc.description.abstractHealth traits are of significant economic importance to the dairy industry due to their effects on milk production and associated treatment costs. Genome-wide association studies (GWAS) provide a means to identify associated genomic variants and thus reveal insights into the genetic architecture of complex traits and diseases. The objective of this study is to investigate the genetic basis of seven health traits in dairy cattle and to identify potential candidate genes associated with cattle health using GWAS, fine mapping, and analyses of multi-tissue transcriptome data.en_US
dc.description.urihttps://doi.org/10.1186/s12864-020-6461-z
dc.identifierhttps://doi.org/10.13016/lxun-qmws
dc.identifier.citationFreebern, E., Santos, D.J.A., Fang, L. et al. GWAS and fine-mapping of livability and six disease traits in Holstein cattle. BMC Genomics 21, 41 (2020).en_US
dc.identifier.urihttp://hdl.handle.net/1903/27105
dc.language.isoen_USen_US
dc.publisherSpringer Natureen_US
dc.relation.isAvailableAtCollege of Agriculture & Natural Resourcesen_us
dc.relation.isAvailableAtAnimal & Avian Sciencesen_us
dc.relation.isAvailableAtDigital Repository at the University of Marylanden_us
dc.relation.isAvailableAtUniversity of Maryland (College Park, MD)en_us
dc.subjectGWASen_US
dc.subjectFine mappingen_US
dc.subjectHealth traiten_US
dc.subjectGene expressionen_US
dc.subjectDairy cattleen_US
dc.titleGWAS and fine-mapping of livability and six disease traits in Holstein cattleen_US
dc.typeArticleen_US

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