Analysis of candidate genes and hypertension in African American adults.

Whitfield, Keith E; Yao, Xiaopan; Boomer, K B; Vogler, George P; Hayward, Mark D; Vandenbergh, David J

Analysis of candidate genes and hypertension in African American adults.

Date

2009

Authors

Citation

Whitfield, Keith E and Yao, Xiaopan and Boomer, K B and Vogler, George P and Hayward, Mark D and Vandenbergh, David J (2009) Analysis of candidate genes and hypertension in African American adults. Ethnicity & disease, 19 (1). pp. 18-22.

DRUM DOI

https://doi.org/10.13016/bjxm-9aac

Abstract

These results extend previous findings of associations of various polymorphisms of ACE to hypertension and support the association of hypertension to the A allele of ACE4. The potential for this polymorphism to alter expression by its position in the gene's promoter region suggests that future studies of altered ACE protein activity are warranted.