miRNA-dysregulation associated with tenderness variation induced by acute stress in Angus cattle

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dc.contributor.authorZhao, Chunping
dc.contributor.authorTian, Fei
dc.contributor.authorYu, Ying
dc.contributor.authorLiu, George
dc.contributor.authorZan, Linsen
dc.contributor.authorUpdike, M Scott
dc.contributor.authorSong, Jiuzhou
dc.date.accessioned2021-10-25T15:32:21Z
dc.date.available2021-10-25T15:32:21Z
dc.date.issued2012-06-01
dc.description.abstractmiRNAs are a class of small, single-stranded, non-coding RNAs that perform post-transcriptional repression of target genes by binding to 3’ untranslated regions. Research has found that miRNAs involved in the regulation of many metabolic processes. Here we uncovered that the beef quality of Angus cattle sharply diversified after acute stress. By performing miRNA microarray analysis, 13 miRNAs were significantly differentially expressed in stressed group compared to control group. Using a bioinformatics method, 135 protein-coding genes were predicted as the targets of significant differentially expressed miRNAs. Gene Ontology (GO) term and Ingenuity Pathway Analysis (IPA) mined that these target genes involved in some important pathways, which may have impact on meat quality and beef tenderness.en_US
dc.description.urihttps://doi.org/10.1186/2049-1891-3-12
dc.identifierhttps://doi.org/10.13016/sjue-znmz
dc.identifier.citationZhao, C., Tian, F., Yu, Y. et al. miRNA-dysregulation associated with tenderness variation induced by acute stress in Angus cattle. J Animal Sci Biotechnol 3, 12 (2012).en_US
dc.identifier.urihttp://hdl.handle.net/1903/28064
dc.language.isoen_USen_US
dc.publisherSpringer Natureen_US
dc.relation.isAvailableAtCollege of Agriculture & Natural Resourcesen_us
dc.relation.isAvailableAtAnimal & Avian Sciencesen_us
dc.relation.isAvailableAtDigital Repository at the University of Marylanden_us
dc.relation.isAvailableAtUniversity of Maryland (College Park, MD)en_us
dc.subjectmiRNAen_US
dc.subjectBovineen_US
dc.subjectBeef tendernessen_US
dc.subjectStressen_US
dc.titlemiRNA-dysregulation associated with tenderness variation induced by acute stress in Angus cattleen_US
dc.typeArticleen_US

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