Fischell Department of Bioengineering
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EFFECTS OF METABOLISM ON MESENCHYMAL STEM CELL-DERIVED EXTRACELLULAR VESICLES
(2020)Mesenchymal stem cells (MSCs) are under investigation for a wide variety of therapeutic applications. It has been determined that paracrine secretions are responsible for a significant portion of MSC bioactivity. Among ... -
HYDROGEL SELECTION AND CIRCUMFERENTIAL VASCULAR SMOOTH MUSCLE CELL ALIGNMENT FOR AN ARTERY-ON-A-CHIP
(2020)Atherosclerosis leads to cardiovascular disease, which is the greatest cause of the death in the US. Atherosclerosis begins with endothelial dysfunction, including reduced nitric oxide production and subsequent vascular ... -
QUANTUM DOT ENCAPSULATED VIRAL LIKE PARTICLES BASED ON ADENO- ASSOCIATED VIRUS
(2020)Adeno-associated virus (AAV) has emerged as a leading gene-therapy candidate due to its broad tissue tropism and encouraging safety profile. Traditionally, viral biodistribution is assessed through expression of reporter ... -
CHARACTERIZATION OF FOCUSED ULTRASOUND BEAM GEOMETRIES USING THERMOCHROMIC LIQUID CRYSTAL FILMS
(2020)Focused ultrasound (FUS) applications are gaining more attention from clinicians for being able to provide effective, non-invasive treatments to almost any region of the body. In-house development of FUS devices require ... -
SPECTRAL X-RAY SCATTERING METHOD FOR IN VIVO ESTIMATION OF AMYLOID BURDEN
(2020)Amyloid-beta plaque deposition in the brain is one of the hallmark features of Alzheimer's disease (AD). Current estimation methods of amyloid burden depend on post-mortem histological analysis or resource-intensive ...