• DEVELOPMENT AND OPTIMIZATION OF A P47-BASED PLASMODIUM VACCINE TO BLOCK MALARIA TRANSMISSION 

  Yenkoidiok-Douti, Lampouguin (2020)

  Malaria is an infectious disease caused by Plasmodium parasites that are transmitted to hosts by infected Anopheles mosquitoes. Over the last two decades, the widespread deployment of effective interventions, such as ...

• IN VIVO BIODISTRIBUTION, LUNG TARGETING, AND PARAMETRIC MODULATION OF A DNA-BASED DRUG DELIVERY SYSTEM ADDRESSED TO ICAM-1 

  Roki, Niksa (2020)

  The design goal of ligand-targeted nanoparticles (NPs) is to achieve site-specific targeting to specific biological targets, which can maximize therapeutic efficacy and safety. However, site-specific delivery remains ...

• ENGINEERING THE LYMPH NODE MICROENVIRONMENT TO MODULATE ANTIGEN-SPECIFIC T CELL RESPONSE 

  Gammon, Joshua Marvin (2019)

  Vaccines and immunotherapies have provided enormous benefit to human health. However, the development of effective vaccines and immunotherapies for many diseases is hindered by challenges created by the complex pathologies ...

• SPRAYABLE, BIODEGRADABLE POLYMER BLENDS FOR TISSUE ADHESION 

  Daristotle, John L (2019)

  Tissue adhesive materials can revolutionize surgical procedures, but they are often difficult to apply safely because of a required curing step where the viscous components of a glue solidify and become sticky. To simplify ...

• Quantitative Phenotyping of Brain Endothelial Cell-Cell Junctions for Physiological and Pathophysiological Applications 

  Gray, Kelsey M (2019)

  The integrity of endothelial cell-cell junctions is required for the maintenance of normal physiological processes. The expression of junctional proteins is particularly important in the endothelial cells of the blood-brain ...

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