Skip to content
University of Maryland LibrariesDigital Repository at the University of Maryland
    • Login
    View Item 
    •   DRUM
    • Theses and Dissertations from UMD
    • UMD Theses and Dissertations
    • View Item
    •   DRUM
    • Theses and Dissertations from UMD
    • UMD Theses and Dissertations
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    APPROACHES TO CHARACTERIZE UBIQUITIN CARBOXY-TERMINAL HYDROLASE L1 BY PROTEOLYTIC MAPPING

    Thumbnail
    View/Open
    umi-umd-3111.pdf (592.3Kb)
    No. of downloads: 780

    Date
    2005-12-13
    Author
    Smith, Natasha Nicole
    Advisor
    Fenselau, Catherine
    Metadata
    Show full item record
    Abstract
    Ubiquitin carboxy-terminal hydrolase-L1 is a member of a class of deubiquitinating enzymes that functions to bind and stabilize ubiquitin, and, thereby, plays a role in the protein degradation of targeted substrates. It is of interest to the research communities in cancer and mental health because of it's suggested roles in neurological disorders and some carcinomas. Here, the recombinant form of this protein is sequenced and characterized using proteomic and mass spectrometry methods. Sixty-nine percent sequence coverage of recombinant UCH-L1 is achieved.
    URI
    http://hdl.handle.net/1903/3283
    Collections
    • Chemistry & Biochemistry Theses and Dissertations
    • UMD Theses and Dissertations

    DRUM is brought to you by the University of Maryland Libraries
    University of Maryland, College Park, MD 20742-7011 (301)314-1328.
    Please send us your comments.
    Web Accessibility
     

     

    Browse

    All of DRUMCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    LoginRegister
    Pages
    About DRUMAbout Download Statistics

    DRUM is brought to you by the University of Maryland Libraries
    University of Maryland, College Park, MD 20742-7011 (301)314-1328.
    Please send us your comments.
    Web Accessibility