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Searching for SNPs with cloud computing

dc.contributor.authorLangmead, Ben
dc.contributor.authorSchatz, Michael C
dc.contributor.authorLin, Jimmy
dc.contributor.authorPop, Mihai
dc.contributor.authorSalzberg, Steven L
dc.identifier.citationLangmead, B., Schatz, M.C., Lin, J. et al. Searching for SNPs with cloud computing. Genome Biol 10, R134 (2009).en_US
dc.description.abstractAs DNA sequencing outpaces improvements in computer speed, there is a critical need to accelerate tasks like alignment and SNP calling. Crossbow is a cloud-computing software tool that combines the aligner Bowtie and the SNP caller SOAPsnp. Executing in parallel using Hadoop, Crossbow analyzes data comprising 38-fold coverage of the human genome in three hours using a 320-CPU cluster rented from a cloud computing service for about $85. Crossbow is available from .en_US
dc.publisherSpringer Natureen_US
dc.subjectSingle Nucleotide Polymorphismen_US
dc.subjectCloud Computingen_US
dc.subjectAdditional Data Fileen_US
dc.subjectWall Clock Timeen_US
dc.subjectHeterozygous SNPsen_US
dc.titleSearching for SNPs with cloud computingen_US
dc.relation.isAvailableAtCollege of Computer, Mathematical & Physical Sciencesen_us
dc.relation.isAvailableAtDigital Repository at the University of Marylanden_us
dc.relation.isAvailableAtUniversity of Maryland (College Park, MD)en_us

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