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HOW SELENIUM MODIFIES CROSS-TALK BETWEEN THE PIKK FAMILY AND INSIGHTS ON THE REGULATION OF DNA-PKcs
We recently found that ATM is required for a selenium-induced senescence response in non-cancerous cells. We hypothesize the selenium-induced DNA damage response modifies ATM and DNA-PKcs cross-talk. Phospho-specific ...
THE ROLE OF ATAXIA TELANGIECTASIA MUTATED AND THE CATALYTIC SUBUNIT OF DNA-DEPENDENT PROTEIN KINASE DURING ADIPOGENESIS
Ataxia telangiectasia mutated (ATM) and DNA-dependent protein kinase catalytic subunit (DNA-PKcs), are DNA damage response (DDR) proteins that have well established roles in the repair of DNA double strand breaks (DSBs). ...