Now showing items 1-4 of 4
ANTICANCER MECHANISM OF TOLFENAMIC ACID IN COLORECTAL CANCER
Colorectal cancer (CRC) is the third leading cause of cancer-related death in the United States. Chemopreventive therapies could be effective way to treat CRC. Tolfenamic acid, one of the NSAIDs, shows anti-cancer activities ...
BIOACTIVE COMPONENTS FROM BLACKBERRIES TO AUGMENT DIETARY APPROACHES TO OBESITY TREATMENT OR PREVENTION: INDIRECT CALORIMETRY STUDIES IN MAN AND TISSUE
Rodent models of diet-induced obesity lead to the discovery of an anti-obesity and anti-diabetic effect of anthocyanins in several forms. In addition to improved body composition and insulin sensitivity, molecular research ...
TRPV4, A CALCIUM-PERMEABLE CHANNEL, PLAYS A ROLE IN MATRIX STIFFNESS INDUCED MACROPHAGE POLARIZATION
Phenotypic polarization of macrophages is deemed essential in innate immunity and various pathophysiological processes, but little is known about how mechanical forces like matrix stiffness regulate the polarization and ...
Identification and functional analysis of a biflavone as a novel inhibitor of TRPV4-dependent atherogenic process in macrophages
Cardiovascular disease is the major cause of death throughout the world. Atherosclerosis, a chronic inflammatory disease of large arteries, is the major contributor to the growing burden of cardiovascular disease-related ...