Now showing items 11-13 of 13
MRP5 AND MRP9 PLAY A CONCERTED ROLE IN MALE REPRODUCTION AND MITOCHONDRIAL FUNCTION
Heme is an essential iron-containing cofactor in proteins that perform diverse functions in biology. Free heme is not only hydrophobic but also generates cytotoxic peroxide radicals. In eukaryotes, heme synthesis occurs ...
Investigating Copper Acquisition And Delivery via Transporters and a Pharmacological Chaperone in Copper-Deficient Worms and Mice
Copper (Cu) is a key micronutrient required for a variety of essential biochemical pathways. Systemic or tissue-specific Cu-deficiencies, caused by insufficient dietary Cu uptake or mutations in Cu transporting genes, ...
The Importance of Transfer Receptor 1 in Adipose Tissue
Iron homeostasis is essential for maintaining cellular function in a variety of cell types. Transferrin receptor 1 (TfR1), which is expressed ubiquitously, facilitates cellular iron (Fe) uptake through receptor-mediated ...