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Heme is an essential cofactor involved in various biological processes including oxygen transport, xenobiotic detoxification, oxidative metabolism, gas sensing, circadian rhythm, signal transduction, microRNA processing ...

Covalent histone modifications constitute a complex network of transcriptional regulation involved in diverse biological processes ranging from stem cell differentiation to immune response. The advent of modern sequencing ...

Reproductive success of the endangered whooping crane (Grus americana) maintained ex situ is suboptimal. The main goals of this multidisciplinary investigation are to advance the understanding of whooping crane reproduction ...

An understanding of the characteristics and regulation of mammary stem cells (MaSCs) is needed to gain insight into normal gland development and carcinogenesis. Previous profiling of MaSCs relied upon immunophenotypic ...

Maternal and cytoplasmic inheritance was investigated in a closed Angus herd. Observed traits were birth weight, weaning weight, adjusted body weight, average daily gain, hock length and scrotal circumference. Each animal ...

Synthesis of the norepinephrine distributed to sub-cortical and cortical brain regions occurs in the locus coeruleus. Impaired function results in reduced availability of norepinephrine. Locus coeruleus degeneration is ...

Cytotoxic T lymphocytes (CTLs) play a critical role in controlling intracellular pathogens and cancer cells, and induction of memory CTLs holds promise for developing effective vaccines against critical virus infections. ...

Polychlorinated biphenyls (PCBs) are a class of synthetic organochlorines that are thermally stable, resistant to degradation, and persistent in the environment as a result of bioaccumulation and intermittent redistribution ...

Neural crest cells (NCCs), a transient, multipotent population of cells that arise during neurulation, are a class of cells crucial to normal vertebrate development. NCCs must be tightly regulated by molecular and structural ...

The objectives of the dissertation research were to determine the role of <italic>denovo</italic> synthesized fatty acids (DNFA) in the regulation of milk fat synthesis. Milk fat responses to increasing amounts of short- ...