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Characterization of Glucocorticoid-Induced Changes in Gene Expression in the Embryonic Pituitary Gland
We have previously shown that corticosterone (CORT) can induce premature differentiation of somatotrophs in the chicken embryo. CORT induction of GH mRNA is indirect, in that protein synthesis inhibition blocks its inducing ...
Effects of Moderate Calorie Restriction on Ovarian Function and Decline in Rhesus Monkeys
Calorie restriction (CR) has long been heralded as the only proven nutritional intervention for life extension. Recent data demonstrated that moderate CR also extended reproductive lifespan in female rats. The objectives ...