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EXPOSURE EFFECTS OF ENVIRONMENTAL GESTAGENS ON THE REPRODUCTIVE BEHAVIOR AND FITNESS OF THE FATHEAD MINNOW (PIMEPHALES PROMELAS)
Historically, endocrine disrupting chemical research has focused on environmental androgens, estrogens, thyroid hormones, and their antagonists. Recent efforts have begun to examine the effects of gestagens, which include ...
OPTIMIZING GENE TARGETING METHODOLOGIES USING CRISPR/CAS RIBONUCLEOPROTEINS IN PORCINE SOMATIC CELLS
The pig is one of the most valuable animal models for agricultural and biomedical research. In this thesis, we sought to standardize procedures for routine gene targeting and demonstrate that it is possible to create ...
Integrative genomic, epigenetic and metabolomic characterization of beef from grass-fed Angus steers
Beef constitutes a main component of the American diet and still represent the principal source of protein in many parts of the world. Currently, the meat market is experiencing an important transformation; consumers are ...
Genetic Suppressors of mrp-5 Lethality in C. elegans
Heme is an essential cofactor in numerous proteins, but is also cytotoxic. Thus, directed pathways must exist for regulating heme homeostasis. C. elegans is a powerful genetic animal model for elucidating these pathways ...