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Now showing items 1-9 of 9
FUNCTIONAL INSIGHTS INTO HRG-1-MEDIATED HEME TRANSPORT
(2012)
Heme is an essential cofactor involved in various biological processes including oxygen transport, xenobiotic detoxification, oxidative metabolism, gas sensing, circadian rhythm, signal transduction, microRNA processing ...
DEVELOPMENT OF ALZHEIMER'S-LIKE PATHOLOGY IN NON-HUMAN PRIMATES WITH REDUCED LEVELS OF NOREPINEPHRINE
(2012)
Synthesis of the norepinephrine distributed to sub-cortical and cortical brain regions occurs in the locus coeruleus. Impaired function results in reduced availability of norepinephrine. Locus coeruleus degeneration is ...
Generating memory cytotoxic T lymphocytes through repetitive peptide boosting
(2012)
Cytotoxic T lymphocytes (CTLs) play a critical role in controlling intracellular pathogens and cancer cells, and induction of memory CTLs holds promise for developing effective vaccines against critical virus infections. ...
THE EFFECTS OF POLYCHLORINATED BIPHEYNLS (PCBs) ON AVIAN CARDIAC DEVELOPMENT
(2012)
Polychlorinated biphenyls (PCBs) are a class of synthetic organochlorines that are thermally stable, resistant to degradation, and persistent in the environment as a result of bioaccumulation and intermittent redistribution ...
The role of the adherens junction protein alphaN-catenin in neural crest-derived trigeminal ganglia formation
(2012)
Neural crest cells (NCCs), a transient, multipotent population of cells that arise during neurulation, are a class of cells crucial to normal vertebrate development. NCCs must be tightly regulated by molecular and structural ...
THE IMPACT OF CULTURE MEDIA ON THE IN VITRO PRODUCTION OF CAT BLASTOCYSTS AND EXPLANT QUALITY
(2012)
Continued improvements in embryo culture media composition allow for the growth of high quality blastocysts, which can be used to derive embryonic stem cells (ESCs). ESCs are capable of becoming any cell type in the body ...
The Potential Role of Milk-Fat-Globule Membrane (MFGM) Proteins in Regulating the Size of Milk-Lipid Droplets
(2012)
The aim of this thesis was to identify protein factors that may regulate the size of lipid droplets in milk. To address this hypothesis, the relative amounts of specific MFGM proteins on lipid droplets fractionated according ...
GENOME-WIDE ANALYSIS OF CHICKEN MIRNAS AND DNA METHYLATION AND THEIR ROLES IN MAREK'S DISEASE RESISTANCE AND SUSCEPTIBILITY
(2012)
Marek's disease (MD) is a T cell lymphoma in chickens and causes high mortality and morbidity in productive chickens. Two inbred chicken lines, resistant line 63 and susceptible line 72, with the same MHC haplotype, showed ...
Characterization and Control of Aggression and Reproduction in the Male Clouded Leopard (Neofelis nebulosa)
(2012)
Clouded leopards are a striking and elusive cat species whose secretive nature has made it difficult to gather information on population statistics and behavior in the wild, where the population is in decline. While captive ...