Disparities in health status and health outcomes exist among subpopulations of women; these disparities may be related to socioeconomic status, race, ethnicity, and country of birth. In this paper, we use surveillance data from 2003 and earlier to examine racial and ethnic differences among women in sexually transmitted diseases (STDs) (chlamydia, gonorrhea, and syphilis), human immunodeficiency virus (HIV), and tuberculosis. We also describe prevention programs the Centers for Disease Control and Prevention (CDC) has developed to address the disparities.