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Shape Analysis of High-throughput Genomics Data
(2015)
RNA sequencing refers to the use of
next-generation sequencing technologies to characterize
the identity and abundance of target RNA species in a biological sample
of interest.
The recent improvement and reduction ...
Analysis and correction of compositional bias in sparse sequencing count data
(Springer Nature, 2018-11-06)
Count data derived from high-throughput deoxy-ribonucliec acid (DNA) sequencing is frequently used in quantitative molecular assays. Due to properties inherent to the sequencing process, unnormalized count data is ...
Simultaneous transcriptional profiling of Leishmania major and its murine macrophage host cell reveals insights into host-pathogen interactions
(Springer Nature, 2015-12-29)
Parasites of the genus Leishmania are the causative agents of leishmaniasis, a group of diseases that range in manifestations from skin lesions to fatal visceral disease. The life cycle of Leishmania parasites is split ...