EVEN THOUGH THE HIV EPIDEMIC IN the United States has shifted increasingly and disproportionately to blacks and Hispanics, a lack of research into prevention strategies tailored to minority communities has impeded efforts to reach these populations. Now, a new initiative launched by the Centers for Disease Control and Prevention (CDC) seeks to help fill such research gaps and to mentor young investigators with ties to these underserved communities. Surveillance data have shown a shift in the demographics and geography of the US HIV/AIDS epidemic. As the proportion of new HIV infections in white men who have sex with men has declined since the epidemic’s early years, about 70% of all new HIV infections now occur among minorities, with blacks accounting for 54% of all new HIV/AIDS diagnoses, according to the CDC. Surveillance statistics in 2002 also show that the greatest expansion of HIV morbidity occurred in Southern states. However, the distribution of research dollars has not matched these demographic and geographic changes in the epidemic.