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Health Care Management System for Diabetes Mellitus: A Model-based Systems Engineering Framework

dc.contributor.advisorBaras, John S.en_US
dc.contributor.authorKatsipis, Iakovosen_US
dc.description.abstractThe present thesis develops a framework for Health Care Management Systems using modern Model-Based Systems Engineering methodologies and applies it to Diabetes Mellitus. The desired architecture of such systems is described. Tests and interventions, including Health Care IT, used for Diabetes 2 diagnosis and treatment, are described and modeled. A Controlled Markov Chain model for the progression of Diabetes Mellitus with three states, three diagnostic tests, ten interventions, three patient types, is developed. Evaluation metrics for healthcare quality and associated costs are developed. Using these metrics and disease models, two methods for tradeoff analysis between healthcare quality and costs are developed and analyzed. One is an exhaustive Monte Carlo simulation and the other utilizes multi-criteria optimization with full state information. The latter obtains similar results as the former at a fraction of the time. Practical examples illustrate the powerful capabilities of the framework. Future research directions and extensions are described.en_US
dc.titleHealth Care Management System for Diabetes Mellitus: A Model-based Systems Engineering Frameworken_US
dc.contributor.publisherDigital Repository at the University of Marylanden_US
dc.contributor.publisherUniversity of Maryland (College Park, Md.)en_US
dc.contributor.departmentSystems Engineeringen_US
dc.subject.pqcontrolledSystem scienceen_US
dc.subject.pqcontrolledPublic healthen_US
dc.subject.pquncontrolledmodel-based systems engineeringen_US
dc.subject.pquncontrolleddecision makingen_US
dc.subject.pquncontrolleddisease progression modelsen_US
dc.subject.pquncontrolledhealth care quality metricsen_US
dc.subject.pquncontrolledcost metricsen_US

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