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Sustaining Interferon Induction by a High-Passage Atypical Porcine Reproductive and Respiratory Syndrome Virus Strain
(Nature Publishing Group, 2016-11-02)
Porcine reproductive and respiratory syndrome virus (PRRSV) strain A2MC2 induces type I interferons in cultured cells. The objective of this study was to attenuate this strain by serial passaging in MARC-145 cells and ...
Inducing Autophagic Cell Death by Nsp5 of Porcine Reproductive and Respiratory Syndrome Virus
(Austin Publishing Group, 2015-11-10)
Porcine Reproductive and Respiratory Syndrome (PRRS) leads to severe economic losses to the swine-producing industry. Many unclear questions remain on pathogenesis of PRRS virus (PRRSV), including the mechanism of PRRSV-induced ...
Interference of Apoptosis by Hepatitis B Virus
(MDPI, 2017-08-18)
Hepatitis B virus (HBV) causes liver diseases that have been a consistent problem for human health, leading to more than one million deaths every year worldwide. A large proportion of hepatocellular carcinoma (HCC) cases ...
Sequence analysis of fusion protein gene of Newcastle disease virus isolated from outbreaks in Egypt during 2006
(2011-05-18)
Background: Newcastle disease virus represents APMV-1 and is the most characterized among all APMV types. The
F protein cleavage site sequence is a well-characterized determinant of NDV pathogenicity in chickens. In ...
Improved hatchability and efficient protection after in ovo vaccination with live-attenuated H7N2 and H9N2 avian influenza viruses
(2011-01-21)
Mass in ovo vaccination with live attenuated viruses is widely used in the poultry industry to protect against
various infectious diseases. The worldwide outbreaks of low pathogenic and highly pathogenic avian ...
Characterization of influenza virus sialic acid receptors in minor poultry species
(2010-12-09)
It is commonly accepted that avian influenza viruses (AIVs) bind to terminal a2,3 sialic acid (SA) residues whereas
human influenza viruses bind to a2,6 SA residues. By a series of amino acid changes on the HA surface ...
VCAM1/VLA4 interaction mediates Ly6Clow monocyte recruitment to the brain in a TNFR signaling dependent manner during fungal infection
(PLoS, 2020-02-26)
Monocytes exist in two major populations, termed Ly6C^hi and Ly6C^low monocytes. Compared to Ly6C^hi monocytes, less is known about Ly6C^low monocyte recruitment and mechanisms involved in the recruitment of this subset. ...
Characterization of tick organic anion transporting polypeptides (OATPs) upon bacterial and viral infections
(Springer Nature, 2018-11-14)
Ixodes scapularis organic anion transporting polypeptides (OATPs) play important roles in tick-rickettsial pathogen interactions. In this report, we characterized the role of these conserved molecules in ticks infected ...
BB0324 and BB0028 are constituents of the Borrelia burgdorferi β-barrel assembly machine (BAM) complex
(Springer Nature, 2012-04-20)
Similar to Gram-negative bacteria, the outer membrane (OM) of the pathogenic spirochete, Borrelia burgdorferi, contains integral OM-spanning proteins (OMPs), as well as membrane-anchored lipoproteins. Although the mechanism ...
Experimental infection of hamsters with avian paramyxovirus serotypes 1 to 9
(Springer Nature, 2011-02-23)
Avian paramyxoviruses (APMVs) are frequently isolated from domestic and wild birds throughout the world and are separated into nine serotypes (APMV-1 to -9). Only in the case of APMV-1, the infection of non-avian species ...