Physics Research Works: Recent submissions

Now showing items 6-10 of 99

    • Data for: Understanding cytoskeletal avalanches using mechanical stability analysis 

      Floyd, Carlos; Levine, Herbert; Jarzynski, Christopher; Papoian, Garegin A. (2021-08)
      Eukaryotic cells are mechanically supported by a polymer network called the cytoskeleton, which consumes chemical energy to dynamically remodel its structure. Recent experiments \textit{in vivo} have revealed that this ...

    • svclassify: a method to establish benchmark structural variant calls 

      Parikh, Hemang; Mohiyuddin, Marghoob; Lam, Hugo Y. K.; Iyer, Hariharan; Chen, Desu; Pratt, Mark; Bartha, Gabor; Spies, Noah; Losert, Wolfgang; Zook, Justin M.; Salit, Marc (Springer Nature, 2016-01-16)
      The human genome contains variants ranging in size from small single nucleotide polymorphisms (SNPs) to large structural variants (SVs). High-quality benchmark small variant calls for the pilot National Institute of Standards ...

    • Evolution of transcriptional networks in yeast: alternative teams of transcriptional factors for different species 

      Muñoz, Adriana; Santos Muñoz, Daniella; Zimin, Aleksey; Yorke, James A. (Springer Nature, 2016-11-11)
      The diversity in eukaryotic life reflects a diversity in regulatory pathways. Nocedal and Johnson argue that the rewiring of gene regulatory networks is a major force for the diversity of life, that changes in regulation ...

    • Internal modifications in the CENP-A nucleosome modulate centromeric dynamics 

      Bui, Minh; Pitman, Mary; Nuccio, Arthur; Roque, Serene; Donlin-Asp, Paul Gregory; Nita-Lazar, Aleksandra; Papoian, Garegin A.; Dalal, Yamini (Springer Nature, 2017-04-04)
      Posttranslational modifications of core histones are correlated with changes in transcriptional status, chromatin fiber folding, and nucleosome dynamics. However, within the centromere-specific histone H3 variant CENP-A, ...

    • Adenylyl cyclase mRNA localizes to the posterior of polarized DICTYOSTELIUM cells during chemotaxis 

      Das, Satarupa; Parker, Joshua M.; Guven, Can; Wang, Weiye; Kriebel, Paul W.; Losert, Wolfgang; Larson, Daniel R.; Parent, Carole A. (Springer Nature, 2017-05-25)
      In Dictyostelium discoideum, vesicular transport of the adenylyl cyclase A (ACA) to the posterior of polarized cells is essential to relay exogenous 3′,5′-cyclic adenosine monophosphate (cAMP) signals during chemotaxis and ...