Now showing items 1-4 of 4
Full-length messenger RNA sequences greatly improve genome annotation
(Genome Biology, 2002-05-30)
Background: Annotation of eukaryotic genomes is a complex endeavor that requires the integration of evidence from multiple, often contradictory, sources. With the ever-increasing amount of genome sequence data now ...
Evidence for symmetric chromosomal inversions around the replication origin in bacteria
(Genome Biology, 2000-12-04)
Background: Whole-genome comparisons can provide great insight into many aspects of biology. Until recently, however, comparisons were mainly possible only between distantly related species. Complete genome sequences are ...
Automated eukaryotic gene structure annotation using EVidenceModeler and the Program to Assemble Spliced Alignments
(Genome Biology, 2008-01)
EVidenceModeler (EVM) is presented as an automated eukaryotic gene structure annotation tool that reports eukaryotic gene structures as a weighted consensus of all available evidence. EVM, when combined with the Program ...
CloVR: A virtual machine for automated and portable sequence analysis from the desktop using cloud computing
(Springer Nature, 2011-08-30)
Next-generation sequencing technologies have decentralized sequence acquisition, increasing the demand for new bioinformatics tools that are easy to use, portable across multiple platforms, and scalable for high-throughput ...