Now showing items 1-3 of 3
Automated eukaryotic gene structure annotation using EVidenceModeler and the Program to Assemble Spliced Alignments
(Genome Biology, 2008-01)
EVidenceModeler (EVM) is presented as an automated eukaryotic gene structure annotation tool that reports eukaryotic gene structures as a weighted consensus of all available evidence. EVM, when combined with the Program ...
A phylogenetic generalized hidden Markov model for predicting alternatively spliced exons
(Algorithms for Molecular Biology, 2006-08-25)
Background: An important challenge in eukaryotic gene prediction is accurate identification of alternatively spliced exons. Functional transcripts can go undetected in gene expression studies when alternative splicing ...
JIGSAW, GeneZilla, and GlimmerHMM: puzzling out the features of human genes in the ENCODE regions
(Genome Biology, 2006-08-07)
Background: Predicting complete protein-coding genes in human DNA remains a significant challenge. Though a number of promising approaches have been investigated, an ideal suite of tools has yet to emerge that can provide ...