Now showing items 1-4 of 4
Searching for SNPs with cloud computing
(Springer Nature, 2009-11-20)
As DNA sequencing outpaces improvements in computer speed, there is a critical need to accelerate tasks like alignment and SNP calling. Crossbow is a cloud-computing software tool that combines the aligner Bowtie and the ...
Comparative analysis reveals signatures of differentiation amid genomic polymorphism in Lake Malawi cichlids
(Springer Nature, 2008-07-10)
Cichlid fish from East Africa are remarkable for phenotypic and behavioral diversity on a backdrop of genomic similarity. In 2006, the Joint Genome Institute completed low coverage survey sequencing of the genomes of five ...
Genome assembly forensics: finding the elusive mis-assembly
(Springer Nature, 2008-03-14)
We present the first collection of tools aimed at automated genome assembly validation. This work formalizes several mechanisms for detecting mis-assemblies, and describes their implementation in our automated validation ...
Comparative genomics of mutualistic viruses of Glyptapantelesparasitic wasps
(Springer Nature, 2008-12-30)
Polydnaviruses, double-stranded DNA viruses with segmented genomes, have evolved as obligate endosymbionts of parasitoid wasps. Virus particles are replication deficient and produced by female wasps from proviral sequences ...