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N-HETEROAROMATIC ACID ADLAYER STRUCTURES UNDER HYDROGEN BONDING INFLUENCE:
(2007-02-20)
In this dissertation, I investigate the adsorption and growth of thin films of N-heteroaromatic acids and related molecules on Ag(111) surface. The N-heteroaromatic acids have ring-nitrogen and carboxylic groups. Hence, ...
A Thermodynamic Investigation into the Allosteric Activation Mechanism of the Biotin Repressor
(2004-11-05)
The biotin regulatory system of Escherichia coli serves as a model for investigating the regulatory mechanism of a non-classical allosteric transcription factor. The central protein, BirA, functions as both an essential ...
Rhodium(II)-Stabilized Vinylcarbenes: Synthetic Applications in Ylide, Cyclopropanation, and C-H Insertion Reactions
(2006-12-07)
A previously unknown cascade reaction in which two units of a rhodium(II)-stabilized vinylcarbene obtained from methyl trans-styryldiazoacetate react with benzylideneaniline is described; the products of the cascade reaction ...
DEGENERATIVE TRANSFER LIVING ZIEGLER-NATTA POLYMERIZATION OF α-OLEFINS
(2005-12-04)
A degenerative transfer (DT) living Ziegler-Natta polymerization system based on the cyclopentadienyl amidinate zirconium complex, (h5-C5Me5)ZrMe2[N(t-Bu)C(Me)N(Et)] (19), has been studied in detail. Compound 19 is an ...
Dynamics and Chemical Shielding in a Small Protein from NMR Spin Relaxation Experiments
(2006-08-04)
NMR spin relaxation spectroscopy is a proven method for characterization of the time-scales and amplitudes of intramolecular motions in proteins. In a typical NMR relaxation experiment, the significant contributions to ...
Study of Wet-Chemically-Prepared Hydrogen-Terminated Silicon (111) Surfaces and a Novel Implementation of a High-Resolution Interferometer
(2004-04-30)
This thesis summarizes my graduate study under the National Institute of Standards and Technology (NIST) Atom-Based Dimensional Metrology Project, in which we are developing methods for measuring sub-micrometer dimensions ...
Synthesis and Characterization of oligosaccharides tethered to gold films and gold nanoparticles
(2004-12-07)
The goal of this research was to stereoselectively synthesize α- and β- linked glucopyranosylamide derivatives utilizing the modified Staudinger methodology and to tether these derivatives to gold films ...
Application of Silicon-Based Cross-Coupling Technology to Aryl Triflates
(2004-05-06)
The goal of this research was to explore the use of aryl silatranes as a replacement for aryl siloxanes in the palladium-catalyzed cross-coupling reaction with aryl triflates. Phenylsilatrane underwent fluoride-induced ...
A GAS-INJECTION NEGATIVE ION SOURCE FOR ACCELERATOR MASS SPECTROMETRY
(2004-11-04)
Accelerator mass spectrometry is an ultra-sensitive isotopic analysis technique that allows for the determination of rare long-lived radionuclides such as radiocarbon. Historically, the technique has required that samples ...
Lipophilic G-Quadruplexes: Structural Studies, Post-Assembly Modification, and Covalent Capture
(2006-08-29)
New nanostructures and functional materials are built through the self-assembly of guanosine. Both the size and regiochemistry of these noncovalent structures are controlled. Lipophilic G-quadruplexes are further stabilized ...