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Fluorescence and NMR Studies of the Role of Metal Ions in HIV-1 Genomic RNA Dimerization and Maturation
(2009)
The dimerization initiation site (DIS) is an essential RNA element responsible for dimerization of HIV-1 genomic RNA through a kissing loop interaction. The DIS loop contains six auto-complementary nucleotides stabilized ...
Reactions of Zintl ion Pb9 with Gold Precursor PPh3AuCl
(2006-12-10)
Transition metal main group clusters have been studied extensively as models for heterogeneous catalysts and metal surface reactions. In this thesis, reactions of Group 14 Zintl ion cluster Pb94- with the Au precursor ...
Airborne Characterization of Regional Aerosol Origins and Optical Properties
(2004-08-31)
The ubiquity of air pollution in the Mid-Atlantic and northeastern U.S. is a major concern for human and ecological health as well as the climate. Between February 2001 and February 2004, 160 flights on a light aircraft ...
SITE-DIRECTED MUTAGENESIS OF GROEL:DEVELOPING A SYSTEM FOR MONITORING ALLOSTERIC MOVEMENTS BY FLUORESCENCE RESONANCE ENERGY TRANSFER
(2007-01-02)
The Escherichia coli chaperonin protein GroEL can assist protein folding to its native state through the consumption of ATP. Accompanying this process, GroEL undergoes structural change, resulting in an expansion of the ...
EXPRESSING DEINOCOCCUS RADIODURANS RECD IN ESCHERICHIA COLI: PHENOTYPIC EFFECTS IN RECBCD(-) AND RECD(-) CELLS
(2006-12-20)
The RecD helicase is a member of the RecBCD complex, which is essential for repair of double-stranded breaks (DSBs) in DNA via homologous recombination in Escherichia coli. The microbe Deinococcus radiodurans is capable ...
Discrete and Polymeric Complexes Comprising Bis-nor-seco-CB[10] and Oligoammonium Ions
(2009)
ABSTRACT
Title of Document: DISCRETE AND POLYMERIC COMPLEXES COMPRISING BIS-NOR-SECO-CB[10] AND OLIGOAMMONIUM IONS
Regan C. Nally, Ph.D., 2009
Directed By: Professor Lyle D. Isaacs
Department of Chemistry and ...
One-Dimensional Free Energy Surface Models of Protein Folding: Connecting Theory and Experiments
(2007-04-27)
Experimental techniques have now reached the sub-microsecond timescale necessary to study fast events in protein folding. However, analysis of fast folding experiments still commonly rely on conventional procedures that ...
Investigation of Shell Model States in Exotic Odd-A Sb Isotopes
(2005-03-23)
The level structures of 134Sb and 135Sb were studied in the b- decays of the very-neutron-rich 134,135Sn isotopes. Tin isotopes were produced by proton- or neutron-induced fission at CERN/ISOLDE and ionized using a resonance ...
Charged Antiparticle to Particle Ratios Near Midrapidity in d+Au and p+p Collisions at sqrt(s_NN) = 200 GeV
(2004-10-28)
Experiments at the Relativistic Heavy Ion Collider (RHIC) at Brookhaven National Laboratory are designed to investigate the behavior of strongly interacting matter at high temperatures and densities. The conditions created ...
PATH-INTEGRAL MONTE-CARLO SIMULATIONS OF ALUMINUM ATOMS EMBEDDED IN SOLID PARA-HYDROGEN AND IN HELIUM CLUSTERS
(2005-05-27)
In this dissertation we use a path-integral Monte Carlo (PIMC) simulation method to study an open-shell atomic Al impurity doped in two kinds of low temperature condensed media.
We first use the Multilevel Metropolis ...