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Now showing items 11-20 of 28
Silencing bacteria with small molecules
(2014)
Quorum sensing (QS) is a phenomenon in bacteria where the accumulation of extracellular signaling molecules (autoinducers, AIs), which enable bacterial cells to sense neighboring cells (population density), reaches certain ...
Exciton Photophysics at Fluorescent Quantum Defects
(2018)
Fluorescent quantum defect is an emerging synthetic structure that can be covalently attached to a semiconducting single-walled carbon nanotube. Incorporation of fluorescent quantum defect breaks the symmetry of carbon ...
ELECTRONIC MODIFICATION WITHIN THE WELL-ESTABLISHED CPAM FRAMEWORK AS A MEANS TOWARD INCREASED REACTIVITY
(2017)
Early transition metals (group IV-VI) supported by the pentamethylcyclopentadienyl-amidinate mixed ligand set (CPAM) have been found to enable a number of important chemical transformations including (living) coordinative ...
Tailoring Guanosine Hydrogels for Various Applications
(2018)
Supramolecular hydrogels are of current interest for their ease of use, potential biocompatibility, and reactivity to stimuli. These gel materials have found use in a number of fields ranging from drug delivery and tissue ...
ENZYME-FREE UBIQUITIN LIGATION. FROM NATIVE CHEMICAL LIGATION AND SPIN LABELING TO DIMERIZATION BY INTER-UBIQUITIN MIMICKING LINKAGE AND PH-DEPENDENT CONFORMATIONAL SWITCH
(2016)
The delicate balance between the production and disposal of proteins is vital for the changes required in the cell to respond to given stimulus. Ubiquitination is a protein modification with a range of signaling outcomes ...
Applications of Photoinduced Electron Transfer Chemistry: Photoremovable Protecting Groups and Carbon Dioxide Conversion
(2016)
Traditional organic chemistry has long been dominated by ground state thermal reactions. The alternative to this is excited state chemistry, which uses light to drive chemical transformations. There is considerable interest ...
Functionalized Acyclic Cucurbit[n]uril Molecular Containers as Reversal Agents for Drugs
(2017)
The study of molecular containers has a prominent place in the scientific literature with many applications, including drug reversal. The clinical use of the cyclodextrin based reversal agent BridionTM has greatly improved ...
APPLIED PHOTOCHEMISTRY FOR MULTICOLOR PHOTOLITHOGRAPHY
(2018)
Photolithography is the most mature technique for nanomanufacturing. Traditional photolithography generates patterns using a single wavelength of light. Recently, there has been considerable interest in the development of ...
ALKYNYL AMINOISOQUINOLINES, NOVEL FLT3 KINASE INHIBITORS WITH POTENT ACTIVITY AGAINST ACUTE MYELOID LEUKEMIA
(2018)
Acute myeloid leukemia (AML) is a type of blood cancer. If not properly treated, this subclass of leukemia can progress quickly, and be fatal after a few months. Aberrantly expressed FMS (Feline McDonough Sarcoma)-like ...
Solid electrolyte interphases on graphite anodes and sulfur cathodes
(2018)
This dissertation describes chemical compositions and fundamental mechanisms of formation of solid electrolyte interphase (SEI) layers on a graphite anode and a microporous carbon/sulfur cathode. Direct analysis on the ...