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Advanced Receptor Models for Exploiting Highly Time Resolved Data Acquired in the EPA Supersite Project
(2012)
Receptor models have been widely used in air quality studies to identify pollution sources and estimate their contributions. A common problem for most current receptor models is insufficient consideration of realistic ...
COMPOUND SPECIFIC CARBON ISOTOPE ANALYSIS FOR BIOMARKERS ASSOCIATED WITH MARINE METHANOTROPHY IN THE ARCTIC
(2012)
A large reservoir of methane exists in marine sediments. The fate of methane is of particular concern in the Arctic, a region that has already demonstrated sensitivity to climate change. The removal of this potent ...
Functional Nanostructure Synthesis and Properties
(2012)
The dissertation addressed challenges in the nanostructure synthesis, applied the materials to engineering fields, such as lithium battery material, fluorescent and magnetic drug deliveries; and developed new characterization ...
Analysis of Intact Proteins in Complex Mixtures
(2013)
Our goal is to develop an effective work flow for analysis of intact proteins in a complex mixture using the LC-LTQ-Orbitrap XL. Intact protein analysis makes the entire sequence available for characterization, which allows ...
ELECTROCHEMICAL SYNTHESIS, TRANSFORMATION, AND CHARACTERIZATION OF MnO2 NANOWIRE ARRAYS FOR SUPERCAPACITOR ELECTRODES
(2013)
The utilization of MnO<sub>2</sub> nanowire arrays for future light weight energy storage devices is investigated here. One of the more specific questions this work looks to answer is: Can ultra high density arrays of ...
New molecules to combat the bacterial antibiotic resistance problem
(2011)
Platensimycin/platencin are recently discovered natural products that inhibit membrane formation in bacteria and cyclic diguanylic acid (c-di-GMP) is a master regulator of bacterial biofilm formation. The rise of bacterial ...
CONDUCTIVE POLYMER NANOTUBE PATCH FOR FAST AND CONTROLLED <italic>IN VIVO</italic> TRANSDERMAL DRUG DELIVERY
(2012)
Transdermal drug delivery has created new applications for existing therapies and offered an alternative to the traditional oral route where drugs can prematurely metabolize in the liver causing adverse side effects. Opening ...
DESIGN AND SYNTHESIS OF AN ELECTRON RICH QUINONE METHIDE PRECURSOR FOR SEQUENCE -DIRECTED ALKYLATION OF DNA
(2012)
Quinone methides (QM) can be delivered to alklyate specific sites with a single strand DNA through target promoted alkylation. Previous experimental results indicated that alkylation by DNA-QM self-adduct was too slow for ...
Synthesis of Functionalized Diazoacetoacetates via Mukaiyama-type Condensations
(2011)
Mukaiyama-type condensation reactions of 3-<italic>tert</italic>-butyldimethylsiloxy-2-diazo-3-butenoate and different electrophiles are effective methods for the synthesis of highly substituted diazoacetoacetates. With ...
Ultrafast nonlinear plasmonics
(2012)
Metal nanostructures can enhance the optical signals by orders of magnitude due to surface plasmon resonance. This field enhancement of the plasmonic nanostructures has led to optical detection and light manipulation beyond ...