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Now showing items 11-20 of 52
Bringing New Chemistry to Guanosine Hydrogels
(2020)
Molecular self-assembly is a powerful method to construct functional materials such as supramolecular hydrogels. Hydrogels contain mostly water but show solid-like rheology. Nucleosides and nucleotides contain rich recognition ...
SYNTHESIS OF PNAG ANALOGS TO PROFILE BIOFILM GLYCOSIDASES
(2021)
Bacteria biofilms consisting of surface-attached bacterial communities embedded in an extracellular matrix serve as a defense mechanism for many medically important bacterial species. Exopolysaccharides of partially ...
Application of Ultrahigh Resolution Mass Spectrometry and Deuterium Labeling to Determine the Contribution of Ketone/ Aldehyde-Containing Species to the Composition and Optical Properties of Dissolved Organic Matter
(2020)
Dissolved organic matter (DOM) is a complex, heterogeneous mixture comprised of thousands of chemical species, found in almost all aquatic environments and is one of Earth’s largest carbon reservoirs. DOM is known to affect ...
DISCOVERY OF A POTENT AND SELECTIVE RIOK1 INHIBITOR ACTIVE IN CRC CELL LINES USING STRUCTURE-BASED DRUG DESIGN
(2021)
Colorectal cancer (CRC) is the second leading cause of cancer-related death in the United State. CRC has aggressive malignancy characterized by poor prognosis and its metastasis and recurrence is the cancer stem cell driven. ...
VAPOR PHASE SYNTHESIS OF ION CONDUCTING AND ION BINDING MATERIALS
(2020)
The ability to generate thin films for energy storage has recently gained a lot of interest. Of the techniques able to do this, molecular layer deposition (MLD) is unique because it allows uniformity, conformality, monolayer ...
EPIGENETICS TUNE CHROMATIN MECHANICS, A COMPUTATIONAL APPROACH
(2021)
The base unit of DNA packaging in eukaryotes, the nucleosome, is adaptively modified for epigenetic control. Given the vast chemical space of chromatin and complexity of signaling and expression, much of our knowledge about ...
FLUORESCENT ULTRASHORT NANOTUBES FROM DEFECT-INDUCED CHEMICAL CUTTING
(2020)
Ultrashort single-walled carbon nanotubes (SWCNTs) that fluoresce brightly in the shortwave infrared shows great potentials in bioimaging, sensing and enabling room-temperature, solid-state single-photon sources. However, ...
Selective filling of n-hexane in a tight nanopore
(Springer Nature, 2021-01-12)
Molecular sieving may occur when two molecules compete for a nanopore. In nearly all known examples, the nanopore is larger than the molecule that selectively enters the pore. Here, we experimentally demonstrate the ability ...
Controlled synthesis of carbon nanotubes: from mechanisms to applications
(2021)
Carbon nanotubes exhibit exceptional properties in many different aspects. However, harnessing those properties in real applications is challenging mainly due to the structural heterogeneity, high impurity contents, and ...
INVESTIGATION OF SOLID-STATE SELF-ASSEMBLY OF ONE- AND MULTI- COMPONENT SUGAR POLYOLEFIN CONJUGATES AND MECHANISMS FOR FRANK-KASPER MESOPHASE TRANSITIONS
(2020)
The self-assembly of molecules provides the basis of life and has become ubiquitous for the development of nanostructured materials. Nanostructured materials have long reaching impacts for the furtherment of science, as ...