Now showing items 151-154 of 154
Investigations of Substrate Recognition of the Biofilm Glycosidase Enzyme Dispersin B
Bacterial biofilms, which are comprised of bacterial cells embedded in a thick extracellular polymeric substance (EPS), is a type of survival mechanism used by a variety of medically relevant bacteria to endure harsh ...
Mechanistic Studies and Rational Catalyst Design of Nickel/Photoredox Dual-Catalyzed C–C Cross-Coupling Reactions
The merging of photoredox and nickel catalysis has revolutionized the field of C–C cross-coupling. However, in comparison to the development of synthetic methods, detailed mechanistic investigations of these catalytic ...
Fluorescent Carbon Nanotubes as Molecular Sensors and Color-Center Hosts
This thesis demonstrates the application of single-walled carbon nanotubes (SWCNTs) as single-digit nanopores for molecular sieving and addresses a fundamental challenge pertaining to controlled synthesis of organic ...
CHEMOENZYMATIC FC GLYCAN ENGINEERING FOR IMPROVING ANTIBODY IMMUNOTHERAPY
IgG antibodies contain a conserved N-glycan on the Fc domain. The structures of the glycan play an important role in modulating an antibody’s effector functions. The Fc N-glycans also provide a suitable site for functionalization ...