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Using Energy Landscape Theory to Uncover the Organization of Conformational Space of Proteins in Their Native States.
(2011)
The functional motions of proteins navigate on rugged energy landscapes. Hence, mapping of these multidimensional landscapes into lower dimensional manifolds is imperative for gaining deeper insights into the functional ...
The Yin and Yang of Amyloids: Insights from alpha-Synuclein and the Pmel17 Repeat Domain
(2011)
While amyloidogenic proteins are commonly associated with human diseases such as Alzheimer's and Parkinson's disease, it is intriguing that amyloid fibrils also are utilized for essential biological processes. A key ...