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Nanofabrication on engineered silicon (100) surfaces using scanning probe microscopy
(2011)
Fabricating and measuring sub-5 nanometer features brings to light several pressing issues in future semiconductor industry manufacturing and dimensional metrology. This dissertation presents a feasible process to create ...
Using Energy Landscape Theory to Uncover the Organization of Conformational Space of Proteins in Their Native States.
(2011)
The functional motions of proteins navigate on rugged energy landscapes. Hence, mapping of these multidimensional landscapes into lower dimensional manifolds is imperative for gaining deeper insights into the functional ...
Equilibrium free energies from nonequilibrium simulations: Improving convergence by reducing dissipation
(2011)
The estimation of equilibrium free energy differences is an important problem in computational thermodynamics, with applications to studies of ligand binding, phase coexistence and phase equilibrium, solvation of small ...
The Yin and Yang of Amyloids: Insights from alpha-Synuclein and the Pmel17 Repeat Domain
(2011)
While amyloidogenic proteins are commonly associated with human diseases such as Alzheimer's and Parkinson's disease, it is intriguing that amyloid fibrils also are utilized for essential biological processes. A key ...