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ELECTROCHEMICAL PROTECTION OF LITHIUM METAL ANODE IN LITHIUM-SULFUR BATTERIES AND BEYOND
(2020)
With the growing demand of advanced energy storage devices that have high energy density and high power density to power electric vehicles and electrical grid, scientists and engineers are exploring technologies beyond ...
DEVELOPMENT OF SINGLE-CELL MASS SPECTROMETRY TOOLS TO INVESTIGATE METABOLIC REORGANIZATION DURING EARLY EMBRYOGENESIS
(2020)
Measurement of metabolism in single cells holds the potential to advance our understanding of fundamental biological processes during cell differentiation and development. However, to characterize the metabolic state of ...
MECHANISTIC STUDY AND THE DESIGN OF IRON-CATALYZED MULTI-COMPONENT CROSS-COUPLING REACTION
(2021)
Cross-coupling reactions (CCRs) are one of the most versatile methods for the formation of C-C bonds. Traditionally, palladium and nickel are broadly used as the catalyst in this type of transformation. However, due to the ...
CHARACTERIZATION OF THE STRUCTURE AND BINDING OF BRANCHED K6/K48-LINKED AND BRANCHED K6/63-LINKED POLYUBIQUITIN CHAINS
(2021)
Ubiquitin (Ub) is an important post-translational protein modifier in eukaryotes. Post-translational modification with Ub is an essential process for eukaryotic cellular signaling including protein degradation, DNA repair, ...
INVESTIGATION OF ORDERED POROUS MATERIALS FOR LITHIUM AND MAGNESIUM IONS ELECTROCHEMICAL ENERGY STORAGE
(2021)
As portable electronics and electric vehicles become a more integral part of everyday life, rechargeable electrical energy storage devices (batteries) capable of providing greater energy and power densities will soon be ...
Bringing New Chemistry to Guanosine Hydrogels
(2020)
Molecular self-assembly is a powerful method to construct functional materials such as supramolecular hydrogels. Hydrogels contain mostly water but show solid-like rheology. Nucleosides and nucleotides contain rich recognition ...
SYNTHESIS OF PNAG ANALOGS TO PROFILE BIOFILM GLYCOSIDASES
(2021)
Bacteria biofilms consisting of surface-attached bacterial communities embedded in an extracellular matrix serve as a defense mechanism for many medically important bacterial species. Exopolysaccharides of partially ...
Application of Ultrahigh Resolution Mass Spectrometry and Deuterium Labeling to Determine the Contribution of Ketone/ Aldehyde-Containing Species to the Composition and Optical Properties of Dissolved Organic Matter
(2020)
Dissolved organic matter (DOM) is a complex, heterogeneous mixture comprised of thousands of chemical species, found in almost all aquatic environments and is one of Earth’s largest carbon reservoirs. DOM is known to affect ...
DISCOVERY OF A POTENT AND SELECTIVE RIOK1 INHIBITOR ACTIVE IN CRC CELL LINES USING STRUCTURE-BASED DRUG DESIGN
(2021)
Colorectal cancer (CRC) is the second leading cause of cancer-related death in the United State. CRC has aggressive malignancy characterized by poor prognosis and its metastasis and recurrence is the cancer stem cell driven. ...
VAPOR PHASE SYNTHESIS OF ION CONDUCTING AND ION BINDING MATERIALS
(2020)
The ability to generate thin films for energy storage has recently gained a lot of interest. Of the techniques able to do this, molecular layer deposition (MLD) is unique because it allows uniformity, conformality, monolayer ...