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Selective Delivery of a Quinone Methide Precursor by Peptide Nucleic Acids
Quinone methides (QMs) are electrophilic intermediates that can be generated in vivo to alkylate DNA and function as anti-cancer drugs. Previously, DNA-QM conjugates have shown the ability to selectively deliver a QM to ...
Theoretical and Experimental Investigations of High Spin Ionic Intermediates
In order to identify high-spin organic intermediates that could potentially be used as building blocks for the construction of high-spin organic ferromagnets, density functional theory (DFT) computations were performed to ...