Now showing items 1-10 of 302
Synthesis and Reactivity of Monohydrocarbyl Palladium(IV) Complexes Using Hydrogen Peroxide as Oxidant in Protic Solvents
Mild, and selective transition metal catalyzed processes for the functionalization of C-H bonds utilizing environmentally benign and inexpensive dioxygen and/ or HOOH oxidants are extremely attractive, as they render these ...
Mechanistic investigations of stoichiometric and catalytic Pt-mediated oxidative functionalization at a proximal boron center
The focus of the work detailed in this dissertation is the investigation of mechanism and catalytic applications of Pt complexes supported by novel anionic di(2-pyridyl)borate ligands. It was found that oxidation of ...
Micelle and Aggregate Formation in Amphiphilic Block Copolymer Solutions
The amphiphilic nature of many block copolymers causes self-aggregation and micelle formation in solvents that are miscible with only one of the block polymers (selective solvents). Micelle and aggregate formation of ...
CATANIONIC SURFACTANT VESICLES: TECHNOLOGY FOR VACCINE DEVELOPMENT AND TARGETED DRUG DELIVERY APPLICATIONS
Catanionic surfactant vesicles have gained attention due to their structural similarities to liposomes and their robust properties in biological media. Catanionic vesicles are formed from oppositely charged surfactants ...
PRINCIPLES OF COMPLEX POLYUBIQUITIN SIGNALING, THE STRUCTURAL BASIS FOR UBIQUITIN-UBISTATIN INTERACTIONS, AND NOVEL ASSAYS FOR THE CHARACTERIZATION OF DEUBIQUITINASES
Ubiquitination is the most versatile and is certainly one of the most difficult post-translation modifications to understand in eukaryotic life. In the process of ubiquitination the C-terminus of ubiquitin (Ub), a small ...
CHEMICAL FUNCTIONALIZATION OF CARBON NANOTUBES FOR CONTROLLED OPTICAL, ELECTRICAL AND DISPERSION PROPERTIES
A carbon nanotube is a graphitic sheet, rolled into a one-dimensional, hollow tube. This structure provides certain individual nanotubes with high conductivity and near-infrared optical activity. These properties are not ...
Synthesis and Application of Double Cavity Cucurbit[n]urils
Molecular containers are a unique set of compounds that are able to recognize and associate with other molecules. It is these molecular recognition properties that has resulted in a large number of research groups studying ...
COMPUTER SIMULATIONS OF PROTEIN FOLDING
Understanding how proteins fold and interact with each other is key to understanding virtually all biological processes. Recent advances in computer power and modeling techniques make it possible to study proteins and other ...
Book of Abstracts: 8th International Symposium on Macrocyclic and Supramolecular Chemistry
This pdf file is the finalized version of the book of abstracts for the 8th International Symposium on Macrocyclic Chemistry held in Arlington, Virginia, USA from July 7-11, 2013
THE DYNAMICS OF DIUBIQUITIN REVEALED BY NMR: WHAT IS THE DRIVING FORCE BETWEEN THE OPEN AND CLOSED STATES?
The K48-linked polyubiquitin chains are important signals for proteasomal degradation and other biological processes. Their recognition of ubiquitin binding partners such as the UBA2 (ubiquitin associated domain 2) domain ...