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A fundamental goal of DNA nanotechnology has been assembly of DNA crystals for use as molecular scaffolds to organize arrays of guest molecules. We use previously described 3D DNA crystals to demonstrate core-shell and ...

Allostery is a biological process in which action, often ligand binding, at one site of the protein alters the function at another site. It provides a mechanism for modulating protein functions in a variety of cellular ...

Bacteriophage CBA120, a member of the Ackermannviridae family, was isolated, sequenced, shown to selectively infect the food pathogen E. coli O157:H7. The CBA120 genome encodes four separate tailspike proteins (TSPs), ...

This thesis details the synthesis and characterization of main group element clusters of Groups 13 (aluminum) and 15 (phosphorus, arsenic). Aluminum clusters were synthesized from metastable Al(I)X (X = Cl, Br) solutions, ...

The oxidation of isoprene – one of the most abundant volatile organic compounds (VOCs) in our atmosphere – significantly impacts the formation of surface ozone, which is detrimental to public health. Computer models simulate ...

Bundled actin structures play a key role in maintaining cellular shape, in aiding force transmission to and from extracellular substrates, and in affecting cellular motility. Recent studies have also brought to light new ...

Atomically precise donor-based quantum devices in silicon are a promising candidate for scalable solid-state quantum computing and analog quantum simulation. This thesis demonstrates success in fabricating state-of-the-art ...

The carbon contained as dissolved organic matter (DOM) in the Earth’s oceans is an important factor in the global carbon cycle, but studying and tracking DOM in the aquatic environment can be challenging. However, the ...

DNA flexibility is important both for fundamental biophysics and because DNA flexibility affects DNA packaging and regulation of gene expression through DNA looping. DNA flexibility has been studied with experiments ranging ...

Non-coding RNAs are involved in various cellular processes and characterization of these RNAs may provide better insights into their functional roles. NMR spectroscopy is a powerful biophysical tool that can provide ...