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The conformational landscape of RNA translational regulators and their potential as drug discovery targets
(2016)
RNA is an underutilized target for drug discovery. Once thought to be a passive carrier of genetic information, RNA is now known to play a critical role in essentially all aspects of biology including signaling, gene ...
Dielectric studies of Liquid Crystal Nanocomposites and Nanomaterial systems.
(2016)
Liquid crystals (LCs) have revolutionized the display and communication technologies. Doping of LCs with inorganic nanoparticles such as carbon nanotubes, gold nanoparticles and ferroelectric nanoparticles have garnered ...
INVESTIGATION OF MAGNESIUM ION CHARGE STORAGE MECHANISM IN MANGANESE DIOXIDE
(2016)
Magnesium (Mg) battery is considered as a promising candidate for the next generation battery technology that could potentially replace the current lithium (Li)-ion batteries due to the following factors. Magnesium possesses ...
AN EXAMINATION OF HYDROXYL RADICAL: OUR CURRENT UNDERSTANDING OF THE OXIDATIVE CAPACITY OF THE TROPOSPHERE THROUGH EMPIRICAL, BOX, AND GLOBAL MODELING APPROACHES
(2016)
Hydroxyl radical (OH) is the primary oxidant in the troposphere, initiating the removal of numerous atmospheric species including greenhouse gases, pollutants that are detrimental to human health, and ozone-depleting ...
End-Group Functionalized Poly(α-olefinates) as Modular Building Blocks
(2016)
The development of living coordination chain transfer polymerization (LCCTP) has provided a viable path to practical and scalable bulk quantities of structurally well-defined polyolefins that are further characterized by ...
Structural characterization of interaction of K11 and K63 mixed-linkage polyubiquitin chains with the tUIMs of epsin1
(2016)
Ubiquitylation or covalent attachment of ubiquitin (Ub) to a variety of substrate proteins in cells is a versatile post-translational modification involved in the regulation of numerous cellular processes. The distinct ...
TOWARD IN SITU MEASUREMENT OF LIQUID DENSITY USING OPTICAL KERR EFFECT SPECTROSCOPY
(2016)
Optical Kerr effect (OKE) spectroscopy is a widely used technique for probing the low-frequency, Raman-active dynamics of liquids. Although molecular simulations are an attractive tool for assigning liquid degrees of freedom ...
Development of Magnetic Nanoparticle-based Enrichment Techniques and Mass Spectrometry Methods for Quantification of the Clinical Biomarker Cardiac Troponin I
(2016)
Human cardiac troponin I (cTnI) in serum is a well-known clinical biomarker for cardiac tissue damage and is used for diagnosing myocardial infarction. Unfortunately, commercial cTnI immunoassays from different manufacturers ...
DESIGN, SYNTHESIS, AND ANTIBODY BINDING STUDIES OF HIV-ASSOCIATED CARBOHYDRATE ANTIGENS
(2016)
The development of an effective prophylactic human immunodeficiency virus (HIV) vaccine is a critical global health priority. However, to-date, all efforts to design an HIV vaccine have been met with a paucity of success. ...
Electrical Properties of a Tube-in-a-Tube Semiconductor
(2016)
Tube-in-a-tube (Tube^2) nanostructures were synthesized through the outer-wall
selective covalent functionalization of double-walled carbon nanotubes (DWCNTs) at
high functional densities. Upon functionalization, the ...