Search
Now showing items 1-10 of 34
Investigation into the Driving Force Dependence of Excess Electron Transport in Duplex DNA
(2009)
The purpose of this dissertation is to investigate the driving force dependence of excess electron transport in deoxyribonucleic acid (DNA) using napthyl amines as electron donors.
The ability of DNA to act as a pathway ...
Efforts Toward Synthesis of Novel Analogs of the Bacterial Second-Messenger, c-di-GMP
(2009)
The formation of bacterial biofilms is a common mechanism for antibiotic resistance. It has been shown that bis-(3'-5')-cyclic dimeric guanosine monophosphate, c-di-GMP, plays a key role in bacterial biofilm formation; ...
Applications of Multiphoton Imaging Techniques To The Study Of Protein Interactions
(2009)
Several recent improvements in microscopy have been driven by advances in ultrafast laser technology. The goal of the research described in this dissertation was to develop noninvasive, optically based methods to measure ...
A Novel Pre-fluorescent Nitroxide Probe for the Highly Sensitive Determination of Peroxyl and Other Radical Oxidants
(2009)
ABSTRACT
Peroxyl and other radical oxidants react with stable cyclic nitroxides, such as the piperidinyl and pyrrolidinyl nitroxides to form initially the one electron oxidation product, the oxoammonium cation. For most ...
SCANNING TUNNELING MICROSCOPY / SPECTROSCOPY STUDIES OF BINARY ORGANIC FILMS
(2009)
Multi-component organic molecular films have seen increasing applications in photovoltaic technologies and other organic electronic applications. These applications have been based upon assumptions regarding film structure ...
Fluorescence and NMR Studies of the Role of Metal Ions in HIV-1 Genomic RNA Dimerization and Maturation
(2009)
The dimerization initiation site (DIS) is an essential RNA element responsible for dimerization of HIV-1 genomic RNA through a kissing loop interaction. The DIS loop contains six auto-complementary nucleotides stabilized ...
Discrete and Polymeric Complexes Comprising Bis-nor-seco-CB[10] and Oligoammonium Ions
(2009)
ABSTRACT
Title of Document: DISCRETE AND POLYMERIC COMPLEXES COMPRISING BIS-NOR-SECO-CB[10] AND OLIGOAMMONIUM IONS
Regan C. Nally, Ph.D., 2009
Directed By: Professor Lyle D. Isaacs
Department of Chemistry and ...
Synthetic Ion Channels From Lipophilic Guanosine Derivatives
(2009)
Synthetic ion channels and pores not only represent models of natural transmembrane ion channels, but also demonstrate their potential applications in the areas of drug delivery, biosensors, antimicrobial agents and other ...
PALLADIUM-CATALYZED ALLYLIC-ARYLATION: MECHANISTIC STUDIES AND APPLICATION TO THE TOTAL SYNTHESIS OF (+/-)-7-DEOXYPANCRATISTATIN DERIVATIVES
(2009)
Palladium-catalyzed carbon-carbon bond formation is one of the most widely used reactions for the synthesis of biologically active substances. The DeShong group has demonstrated that hypervalent silicates can be employed ...
MULTIPHOTON ABSORPTION: FABRICATION, FUNCTIONALIZATION AND APPLICATIONS
(2009)
Despite the remarkable progress in micro/nano-scale fabrication that has occurred over the last decades, feature sizes are still restricted by the diffraction limit. The resolution in conventional photolithography is ...