Browsing Chemistry & Biochemistry by Author "McMahon, James B"

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    • Griffithsin tandemers: flexible and potent lectin inhibitors of the human immunodeficiency virus 

      Moulaei, Tinoush; Alexandre, Kabamba B; Shenoy, Shilpa R; Meyerson, Joel R; Krumpe, Lauren RH; Constantine, Brian; Wilson, Jennifer; Buckheit, Robert W Jr.; McMahon, James B; Subramaniam, Sriram; Wlodawer, Alexander; O’Keefe, Barry R (Springer Nature, 2015-01-23)
      The lectin griffithsin (GRFT) is a potent antiviral agent capable of prevention and treatment of infections caused by a number of enveloped viruses and is currently under development as an anti-HIV microbicide. In addition ...