Browsing Chemistry & Biochemistry by Title
Now showing items 378-397 of 553
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Pressure Tuning the Topology of Quantum Materials
(2019)Topological materials have attracted great interest in condensed matter physics because of their potential applications for topological quantum computing. Transition metal dichalcogenides are very promising topological ... -
PRINCIPLES OF COMPLEX POLYUBIQUITIN SIGNALING, THE STRUCTURAL BASIS FOR UBIQUITIN-UBISTATIN INTERACTIONS, AND NOVEL ASSAYS FOR THE CHARACTERIZATION OF DEUBIQUITINASES
(2013)Ubiquitination is the most versatile and is certainly one of the most difficult post-translation modifications to understand in eukaryotic life. In the process of ubiquitination the C-terminus of ubiquitin (Ub), a small ... -
PRINCIPLES OF INFORMATION PROCESSING IN NEURONAL AVALANCHES
(2011)How the brain processes information is poorly understood. It has been suggested that the imbalance of excitation and inhibition (E/I) can significantly affect information processing in the brain. Neuronal avalanches, a ... -
A Probe of Colored Medium Effects on Quarkonia Polarization in √s = 7 TeV pp collisions at CMS
(2017)The suppression of quarkonia mesons is one of the signature indications of the presence of a quark-gluon plasma, the colored, asymptotically free state of matter believed to have existed moments after the Big Bang, and ... -
Probing Allosteric Communication Between Disordered Surfaces in a Protein
(2015)Molecular mechanisms of protein allostery are not well understood, particularly in those systems that undergo disorder to order transitions upon activation. BirA, an E.coli metabolic enzyme and transcriptional repressor, ... -
PROBING ATMOSPHERIC AEROSOL AND GAS PROPERTIES WITH PHOTOACOUSTIC SPECTROSCOPY
(2011)Absorption by atmospheric aerosols is the wild card for global climate change. Issues regarding atmospheric gases and aerosols have been at the forefront and the work presented within is directed at those issues. ... -
Problem Sets for Organic Spectroscopy
(2018)This folder contains organic structural spectroscopy problems used by Dr. Isaacs in his Chemistry 460 course at the University of Maryland. Each problem contains 1H, 13C, DEPT, COSY, HSQC, and HMBC NMR spectra that were ... -
PROTEIN FOLD SWITCHING: INVESTIGATING THE MECHANISM OF αβ-PLAIT TO 3α FOLD INTERCONVERSION
(2019)Naturally occurring metamorphic proteins have the ability to interconvert from one folded state to another through either a limited set of mutations or by way of a change in the local environment. However, the design of ... -
Protein folding and amyloid formation in various environments
(2008-11-21)Understanding and predicting the effect of various environments that differ in terms of pH and the presence of cosolutes and macromolecules on protein properties is a formidable challenge. Yet this knowledge is crucial in ... -
PROTEOME ANALYSIS OF FORMALIN-FIXED AND PARAFFIN-EMBEDDED TISSUE
(2008-04-04)Because of the long history of the use of formalin as the standard fixative for tissue processing in histopathology, these archival formalin-fixed and paraffin-embedded (FFPE) tissues present invaluable resources for ... -
Proteomic Analysis of Plasma Membrane Proteins from Drug Susceptible and Drug Resistant Breast Cancer Cell Lines
(2004-11-08)Drug discovery is an important field of research in the biotechnology and pharmaceutical industries. Plasma membranes are rich in drug targets and other proteins responsible for cell signaling, transport, signal transduction, ... -
PROTEOMIC CHARACTERIZATION OF EXOSOMES SHED BY MYELOID-DERIVED SUPPRESSOR CELLS
(2015)Exosomes are a class of extracellular vesicles that have been shown to contribute to metastasis when derived from tumor cells. Myeloid-derived suppressor cells (MDSC) are an immature population of myeloid cells that ... -
PURIFICATION AND CHARACTERIZATION OF THE RECD PROTEIN-HOMOLOGUE FROM DEINOCOCCUS RADIODURANS
(2004-12-06)In many gram-negative bacteria, RecBCD enzyme is found to be responsible for double strand DNA break repair through homologous recombination. The AddAB enzyme, a RecBCD analog, is found in some gram-positive bacteria and ... -
Purple Pepper Plants, An Anthocyanin Powerhouse: Extraction, Separation and Characterization
(2014)ABSTRACT Title of Dissertation: PURPLE PEPPER PLANTS, AN ANTHOCYANIN POWERHOUSE: EXTRACTION, SEPARATION AND CHARACTERIZATION Cassandra Lynn Taylor Doctor of Philosophy, 2014 Dissertation ... -
QUANTIFYING PARTICLE PROPERTIES FROM ION-MOBILITY MEASUREMENTS
(2012)Nanoparticles have received considerable interest due to the wide variety of potential applications in biomedical, optical, and electronic fields. However, our capabilities for quantitatively charactering these materials, ... -
QUANTIFYING THE EMISSIONS OF CARBON DIOXIDE (CO2), CARBON MONOXIDE (CO), AND NITROGEN OXIDES (NOx) FROM HUMAN ACTIVITIES: TOP-DOWN AND BOTTOM-UP APPROACHES
(2021)This dissertation encompasses three projects that quantify the emissions of greenhouse gases and air pollutants from human activities. In the first project, we use the aircraft-based mass balance (MB) approach to quantify ... -
QUANTITATIVE ANALYSIS OF INTACT PROTEINS AND RNAS CARRIED BY IMMUNOSUPPRESSIVE EXOSOMES
(2016)Myeloid-derived suppressor cells (MDSC) are immature myeloid cells that accumulate in the tumor microenvironment of most cancer patients. They are a major obstacle to immunotherapy because they suppress both adaptive and ... -
QUANTITATIVE ANALYSIS OF THE ATMOSPHERIC OXIDATION OF ISOPRENE USING MODELS AND MEASUREMENTS: IMPACTS ON SURFACE OZONE
(2019)The oxidation of isoprene – one of the most abundant volatile organic compounds (VOCs) in our atmosphere – significantly impacts the formation of surface ozone, which is detrimental to public health. Computer models simulate ... -
QUANTITATIVE ASSESSMENT OF BIS(2-ETHYLHEXYL) PHTHALATE IN COMMONLY-CONSUMED FOODS AND ELUCIDATION OF ITS NATURAL COMPONENT IN STILTON CHEESE BY COMPOUND-SPECIFIC CARBON ISOTOPE ANALYSIS
(2013)Bis(2-ethylhexyl) phthalate (DEHP) is classified as a "priority hazardous substance" by the European Union, a probable human carcinogen by the United States Environmental Protection Agency, and is a suspect human endocrine ... -
Quantum mechanical investigation on the vibrational relaxation of HF in collisions with H atoms
(2007-05-10)We investigate the vibrational relaxation of HF(v=2-5) in collisions with H atoms by means of fully-quantum reactive scattering calculations. Our calculations are based on the global ab initio potential energy surface of ...