UMD Theses and Dissertations

Permanent URI for this collectionhttp://hdl.handle.net/1903/3

New submissions to the thesis/dissertation collections are added automatically as they are received from the Graduate School. Currently, the Graduate School deposits all theses and dissertations from a given semester after the official graduation date. This means that there may be up to a 4 month delay in the appearance of a given thesis/dissertation in DRUM.

More information is available at Theses and Dissertations at University of Maryland Libraries.

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Author: search.filters.author.Chang, Jonathan Paul

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    ACCELERATED SELF-ASSEMBLY OF PEPTIDE-BASED NANOFIBERS USING NANOMECHANICAL STIMULUS
    (2010) Chang, Jonathan Paul; Seog, Joonil; Material Science and Engineering; Digital Repository at the University of Maryland; University of Maryland (College Park, Md.)
    One-dimensional nanostructures are ideal building blocks for functional nanoscale assembly. Peptide-based nanofibers have great potential for building smart hierarchical structures due to their tunable structures at a single residue level and their ability to reconfigure themselves in response to environmental stimuli. In this study, it was observed that a pre-adsorbed silk-elastin-based protein polymer self-assembled into nanofibers through a conformational change on the mica substrate. Furthermore, using atomic force microscopy, it was shown that the rate of the self-assembling process was significantly enhanced by applying a nanomechanical stimulus. The orientation of the newly grown nanofiber was mostly perpendicular to the scanning direction, implying that the new nanofiber assembly was locally activated with a directional control. The method developed as a part of this study provides a novel way to prepare a nanofiber patterned substrate using a bottom-up approach.