The current dissertation addresses the central nervous system (CNS) strategies to solve kinetic redundancy in multi-digit static prehension under different geometries of hand-held objects and systematically varied mechanical constraints such as translation and rotation of the hand-held object. A series of experiments conducted for this dissertation tested the following hypotheses suggested in the current literatures for multi-digit human static prehension: Hierarchical organization hypothesis, principle of superposition hypothesis, proximity hypothesis, and mechanical advantage hypothesis. (1) Forces and moments produced by fingers during circular object prehension were grouped into two independent subsets: one subset related to grasping stability control and the other associated with rotational equilibrium control. This result supports the principle of superposition hypothesis. Individual fingers acted synergistically to compensate each other's errors. This result confirms the hierarchical organization hypothesis in circular object prehension. (2) During fixed object prehension of a rectangular object, the closer the non-task fingers positioned to the task finger, the greater the forces produced by the non-task fingers. However, during free object prehension, the non-task fingers with longer moment arms produced greater forces. The former and latter results support the proximity hypothesis and the mechanical advantage hypothesis, respectively. (3) The grasping stability control and rotational equilibrium control were decoupled during fixed object prehension as well as free object prehension. This result supports the principle of superposition hypothesis regardless of the mechanical constraints provided for these two prehension types. (4) During torque production, the fingers with longer moment arms produced greater forces when the fingers acted as agonists for the torque production. Therefore, the mechanical advantage hypothesis was supported for agonist fingers. (5) Coupling of thumb normal force and virtual finger normal force was not necessitated when horizontal translation of hand-held object was mechanically fixed. However, the coupling of two normal forces was always observed regardless of given translational constraints, and these two normal forces were independent to other mechanical variables such as tangential forces and moments. This result supports the principle of superposition hypothesis in static prehension under varied combinations of translational constraints.