This paper will present the research results from developing a computer database system using a variant design approach to assist in the preparation of quality manuals. The basic principle is "the most common one of design assignments modifies or uses an existing design to make a 'new' component." Such an information flow mainly relies on a database, which stores all the information about ISO 9000 certification requested by a desired company. Integration of system architecture and communication protocol allows to accommodate different types of business (electronics, mechanical, etc.). A case study is presented to illustrate the process of generating quality manuals through an intelligent user-interface and to demonstrate a new and unique business strategy to enhance quality improvement and management.