An algorithm is presented to automatically determine the relative 3D positions of audio sensors and actuators in an ad-hoc distributed network of heterogeneous general purpose computing platforms. A closed form approximate solution is derived, which is further refined by minimizing a non-linear error function. Our formulation and solution accounts for the lack of temporal synchronization among different platforms. We also derive an approximate expression for the mean and covariance of the implicitly defined estimator. The theoretical performance limits for the sensor positions are derived and analyzed with respect to the number of sensors and actuators as well as their geometry. We report extensive simulation results and discuss the practical details of implementing our algorithms.