This dissertation explores the query optimization technique of using cached results and feedback for improving performance of database systems. Cached results and experience obtained by running queries are used to save execution time for follow–up queries, adapt data and system parameters, and improve overall system performance. First, we develop a framework which integrates query optimization and cache management. The optimizer is capable of generating efficient query plans using previous query results cached on the disk. Alternative methods to access and update the caches are considered by the optimizer based on cost estimation. Different cache management strategies are also included in this framework for comparison. Empirical performance study verifies the advantage and practicality of this framework. To help the optimizer in selecting the best plan, we propose a novel approach for providing accurate but cost-effective selectivity estimation. Distribution of attribute values is regressed in real time, using actual query result sizes obtained as feedback, to make accurate selectivity estimation. This method avoids the expensive off-line database access overhead required by the conventional methods and adapts fairly well to updates and query locality. This is verified empirically. To execute a query plan more efficiently, a buffer pool is usually provided for caching data pages in memory to reduce disk accesses. We enhance buffer utilization by devising a buffer allocation scheme for recurring queries using page fault feedback obtained from previous executions. Performance improvement of this scheme is shown by empirical examples and a systematic simulation.